"Our findings revealed profound chromatin, transcriptomic, and cellular alterations affecting neuronal and glial cells in focal cortical dysplasia (FCD) lesions, including the selective loss of upper-layer excitatory neurons, significant expansion of oligodendrocytes and immature astrocytic populations, and a distinct neuronal subpopulation harboring dysmorphic neurons. Furthermore, we uncovered activated microglia subsets, particularly in FCD IIb cases."
https://www.cell.com/iscience/fulltext/S2589-0042%2824%2902562-8
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