Comment by 🚀 stack

=> Re: "Obviously" | In: u/AsherFisc

Depleted cheese receptors are a major cause of depression, according to my (yet unpublished) data, and may lead to other unpleasant outcomes.

Sheep cheeses appear to cause stronger withdrawal symptoms.

=> 🚀 stack

2024-12-10 · 6 weeks ago

Poll Results

1. I would eat aged cheese while taking the antidepressant drug phenelzine.

████████████▁▁▁▁▁▁▁▁▁▁▁▁ 50%

2. I would eat cheese while taking the anxiolytic drug alprazolam despite the risk of addiction.

████████████▁▁▁▁▁▁▁▁▁▁▁▁ 50%

6 votes were cast.

6 Later Comments ↓

=> 🐰 AsherFisc [OP] · Dec 10 at 16:40:

@satch Yes. Phenelzine's mechanism of action makes you vulnerable to adverse effects from certain foods. This mainly includes food high in tyramine, like cheese and wine. Phenelzine inhibits the enzyme that breaks tyramine down, so it leads to too much tyramine in your body, which then leads to a hypertensive crisis. The MAOI class of antidepressants, which phenelzine is a part of, are well known to cause this effect. This is why they are not widely used anymore. Unfortunately, MAOIs seem to have a quicker onset of effects, while the newer antidepressant classes are usually much slower.

=> 🖥️ mrrobinhood5 · Dec 10 at 17:21:

can you dumb it down for the lay men such as myself?

=> 🐰 AsherFisc [OP] · Dec 10 at 20:01:

Yes. Basically, there’s a chemical compound (tyramine) in cheese that our body is supposed to break down when we consume it. Phenelzine stops the body from breaking down that compound (tyramine), so the concentration of it rises too high. This leads to your blood pressure rising very high—dangerously high.

=> 🕹️ skyjake [...] · Dec 11 at 05:10:

Option 3: there is no longer cheese on the floor. I have a dog...

=> 🌻 hyol · Dec 13 at 10:41:

Is there a risk of addiction with diazepam and lorazepam as well?

=> 🐰 AsherFisc [OP] · Dec 14 at 01:59:

All of the benzodiazepines, including diazepam, lorazepam, alprazolam, clonazepam, temazepam, and many others have the potential to cause addiction and physical dependence.

Original Post

=> 🐰 AsherFisc

Obviously — There is cheese on the floor!

=> 💬 8 comments · 2024-12-10 · 6 weeks ago · #alprazolam #antidepressant #anxiolytic #cheese #drugs #phenelzine 🗳️ #Xanax