A group led by the Department of Neurosurgery, Brain Research Institute, Niigata University succeeded in the diagnosis of leptomeningeal disease in diffuse midline gliomas by detecting H3K27M-mutant droplets from circulating tumor DNA of cerebrospinal fluid taken from these patients.
https://www.news-medical.net/news/20250127/Early-detection-of-tumor-spread-improves-treatment-outcomes.aspx
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