Ancestors

Written by Doc Impossible on 2025-01-22 at 21:20

A small, friendly reminder:

Injectable hormones are suspended in ~~castor oil~~ a carrier oil. ~~Castor oil~~ Carrier oils are really good at keeping those hormones dissolved.

But ~~castor oil~~ carrier oils go rancid over the course of a few years, depending on what type they are. Faster if you don't keep it in a dark place. And rancid ~~castor oil~~ carrier oils don't work properly, and can even hurt you.

So, please keep an eye on the expiration date of any vial of hormones you have or get, and discard anything past its expiration date promptly.

Because you can't tell if ~~castor oil~~ carrier oils have gone rancid by sight. Only smell or texture.

And you can't smell or feel it in a sealed vial.

Edit: I was not entirely correct here--injectable hormones use a variety of oils, some of which are longer-lived than castor.

That being said, the core point remains: Please take the expiration dates on your injectable hormones seriously, especially if you have other comorbidities that can interact with injections.

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Written by Shannon McKinnion on 2025-01-22 at 21:28

@Impossible_PhD - If I remember

Estradiol valerate uses castor oil, (sometimes sesame oil)

Estradiol cypionate uses cottonseed oil.

That being said, they both have roughly 12-24 months and really like a cool dark place.

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Written by Doc Impossible on 2025-01-22 at 21:43

@shannon_mck I was pretty sure cyp used castor oil. Almost all Injectables do.

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Written by Shannon McKinnion on 2025-01-22 at 22:07

@Impossible_PhD - I doublechecked the formulary, and I can't find castor oil in cyp. (and one of the reasons I was given for why cyp takes longer to break down is because it's not castor).

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Written by Doc Impossible on 2025-01-22 at 22:16

@shannon_mck mmmm from the data sheets I can find, cottonseed oil goes rancid faster that castor, not slower. Max tested life before rancidity was just under 650 days, from the Science Direct source I found.

I'd love a source that says otherwise.

EDIT: Someone found information showing otherwise. Please disregard this!

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Written by Shannon McKinnion on 2025-01-22 at 22:27

@Impossible_PhD - So would I. I've been using the 12-24 month as a baseline for my stockpile, but if it's lower, I'm going to want to refigure out things.

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Written by Doc Impossible on 2025-01-22 at 22:40

@shannon_mck I can't find a definitive statement on Pfizer EC. This is their MSDS, and it doesn't address it.

Mind checking the expiry on your vials? The suggestions I've been able to find (poor source strength) says they dare them for 6-12 months from manufacture (and, if so, the shorter shelf life would explain why there seem to be shortages of EC so much more often than EV).

https://pfe-pfizercom-prod.s3.amazonaws.com/products/material_safety_data/estradiol_cypionate_inj_6-June-2019.pdf

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Toot

Written by Shannon McKinnion on 2025-01-22 at 22:41

@Impossible_PhD - I will do that! (I'm in the lab right now, saying Very Bad Words to ArcGIS)

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