I’m going to need you to read all of this and consider the possibility that you’re not educated enough to make finite determinations on the validity of someone else’s gender. The simple fact is, it’s of no consequence to you, but if you somehow feel it is, know that you’re too ignorant for it to be. 💋
[#]Trans #Gender #Intersex #NonBinary #DNA #EnoughIsEnough
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ChristopherE on Bluesky writes:
In 1890, the X and Y chromosomes were discovered. It was found that the men who were tested had 46 chromosomes, including an X and a Y, while women who were tested also had 46 chromosomes, including 2 X chromosomes.
So obviously the conclusion was that the Y chromosome defined masculinity.
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@Addmen ChristopherE on Bluesky:
A reasonable conclusion.
Fast forward 50 years... and it was found that some men had 47 chromosomes, including 2 X's and a Y, while some women had 45, including only one X. Still no problem with the "Y chromosome defines masculinity" idea.
2/12
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@Addmen ChristopherE on Bluesky:
Then... it was found that fully 1 in 300 men weren't 46,XY. Some women were. Oops.
After DNA was discovered in the 50s, it was found that the SrY gene, usually found on the Y chromosome, sometimes was missing.
And sometimes had been translocated to another chromosome, hence 46,XX men and 46,XY women
3/12
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@Addmen ChristopherE on Bluesky:
So SrY defined masculinity.
Then.. it was found out that some men didn't have an Sry chromosome, not anywhere.
Some women did. Other genes were involved. Worse, other factors, such as Androgen Insensitivity made 46,XY people female, and Congenital Adrenal Hyperplasia masculinised 46,XX people.
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@Addmen ChristopherE on Bluesky:
Then in the 70s, other syndromes, such as 5alpha-reductase-2 deficiency were identified, which caused babies to look like one sex at birth, then the other at puberty.
Worse, in some places 1 in 50 infants had this natural sex change, it was not rare there.
5/12
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@Addmen ChristopherE on Bluesky:
Science 1974 Dec 27; 186 (4170): 1213-5
In an isolated village of the southwestern Dominican Republic, 2% of the live births were in the 1970's, guevedoces....These children appeared to be girls at birth, but at puberty these 'girls' sprout muscles, testes, and a penis.
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@Addmen ChristopherE on Bluesky:
For the rest of their lives they are men in nearly all respects.
In the 90s, it was found that hormonal hiccups in the womb caused some parts of the body to develop as one sex, others as the other, regardless of genetics.
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@Addmen ChristopherE on Bluesky:
Male-to-female transsexuals have female neuron numbers in a limbic nucleus. Kruiver et al J Clin Endocrinol Metab (2000)
85:2034-2041
The present findings of somatostatin neuronal sex differences in the BSTc and its sex reversal in the transsexual brain
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@Addmen ChristopherE on Bluesky:
clearly support the paradigm that in transsexuals sexual differentiation of the brain and genitals may go into opposite directions
It's a matter of timing during foetal development. Sometimes a boy is born looking like a girl, sometimes a girl is born looking like a boy, regardless of chromosomes.
9/12
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@Addmen ChristopherE on Bluesky:
This is complex stuff. We don't teach the Theory of General Relativity in grade school, Newtonian physics or at most Special Relativity (far simpler) is enough. Similary,
"XX is female, XY is male" is good enough unless you do medicine or biology in college.
10/12
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@Addmen ChristopherE on Bluesky:
It's only really relevant when talking about Trans or Intersex people, just as Relativistic effects only become relevant in the domain of the very big, very small, or very very fast, close to 186,000 miles a second.
11/12
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@Addmen ChristopherE on Bluesky:
People do not need psychiatric help when they think that things get heavier, more massive, as they go faster... while lengths contract. People do not need help when they think their sex is something different from their genetics.
12/12
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@Addmen This was past my full comprehension, but it was fascinating. My knowledge of the existence of Turner Syndrome(which affects 1 X chromosome people) was one of the first things I thought of when the topic of trans started to become mainstream and prominent in recent years. Just that small bit of information took me to the next step of thinking that sex and gender are probably more complicated than we might have thought.
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@shannonkay @Addmen
Not to forget sex- / gender-related preferences concerning any partners.
Of course this aspect can get very weird if talking about abuse inside the church or pedophilia.
Furthermore it might be conditioned by environment very much.
Nevertheless it's probably a very vital decision especially for people who never define themselves as cis-gender or who just can't be defined clearly as man or woman by known classification.
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text/gemini
