January 12, 2025- “The hygiene hypothesis is being eroded
Infections at a young age correlate with severe infections later in life, few infections in youth correlate with less infections in adulthood
Where was the “strengthening of kids immune system” from infections?” - AJ Leonardi, MBBS, PhD (01/06/25) - https://www.cidrap.umn.edu/antimicrobial-stewardship/early-life-infection-burden-continues-throughout-childhood-new-data
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@Brad It seems that several things got conflated in this nutty "hygiene hypothesis" - Viruses vs. Bacteria most obviously.
There are lots and lots of good bacteria - you're literally stuffed with them. There aren't any good viruses.
All the studies I've ever seen on healthy exposures in children are on BACTERIA. (e.g. the evidence in favor of mothers being exposed to farmyards while the child is in utero & under 2 - greatly reduces adult incidences of immune dysfunction)
But they pivoted pretty damn hard once they faced a virus that they couldn't eradicate without costing the managerial class too much.
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@subjacentish @Brad THIS 👆
oh and hey, viruses are oncogenic
HPV » cervical, penis, anus, vagina, vulva, and mouth and throat cancers
Epstein-Barr » stomach cancer, Hodgkin lymphoma, fast-growing lymphomas, nasopharyngeal cancer, MS
Hepatitis B & C » liver cancer
HIV » Kaposi sarcoma, cervical cancer, Liver cancer, Hodgkin disease, Lung cancer, Cancers of the mouth and throat
HPV 8 » Kaposi sarcoma
HTLV-1 » non-Hodgkin lymphoma
MCV » skin cancer
and, of course, SARS-CoV-2
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@dank
Do we have any data yet that suggests that COVID is carcinogenic? (I'm not saying it isn't, I'd just like to know what we see so far)
@subjacentish @Brad
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@notsoloud @dank @Brad Arijit Chakravarty (@arijitchakrav https://x.com/arijitchakrav) is the guy you wanna look at. I posted a thread of his awhile back somewhere.
TLDR is that it's very hard to get a virus categorized as "Carcinogenic" and they don't understand the carcinogenic properties of viruses very well at all. Strong links, and it sounds like he thinks it will be eventually ruled a carcingen officially.
In the meantime, Covid also downregulates and damages the parts of your immune system that clean up cancer cells. Meaning the cancer you have (most of us have some cancer cells @ a given time) may become suddenly aggressive. This is likely what's behind so many people's sudden Stage IV... I've lost 5 people in the last 2 years to Sudden Stage IV cancers. Lung, Neuro-Endocrine, Ovarian. All were under the age of 50.
A general review is here:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11441415/
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@subjacentish @notsoloud @Brad
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