All external communications with #NIH have been shut down by executive order.
One of my colleagues was in the middle of an F99/K00 (specialized transition grant from grad school to postdoc for marginalized students) and the study section was shut down in the middle of the meeting.
Unclear what this means. Just passing on information.
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Radio Canada (Les années lumière) did a report on our "robot apocalypse / anxiety" paper. (En français.)
https://ici.radio-canada.ca/ohdio/premiere/emissions/les-annees-lumiere/episodes/949747/rattrapage-dimanche-19-janvier-2025
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Why economists need to know the neuroscience
The talk I gave at the APEC applied economics) group at UMN is now up on #youtube.
https://www.youtube.com/watch?v=v1jZxG-0EsA
[#]AppliedEconomics #neuroecononomics #sne
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New paper is out in #plosbiology !
Dorsal hippocampus represents locations to avoid as well as locations to approach during approach-avoidance conflict
Olivia Calvin et al. 2025
PLoS Biology 23(1): e3002954.
After being attacked by a robot, new place fields appear, not at the location of the rat when attacked (which is what "episodic memory" theories would predict), but rather at the location of the robot. Then, when the rat shows signs of being worried about being attacked by the robot, those cells are active and the hippocampus decodes to the robot's location.
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002954
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@pluralistic
How does that "individual pricing in grocery stores" work? Does that mean the price can change from the time you take it off the shelf to the time you check out? How does that match the "economic agreement"? (which depends on full information on both sides).
At least airplane and online store prices lock in the individual price when you select it. It doesn't suddenly change at the payment page. Although, I'm sure that's the next enshitification step...
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[#]neuroscience #hippocampus #historyOfScience
It looks like the hippocampal special issue on "Scientific Histories of Hippocampal Research" is fully out. These are fantastic. I recommend reading them all!
https://onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)1098-1063.scientific-histories-hippocampal-research
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It looks like I missed last year. So I've also opened the 2022 ones. (4/4)
S. Vinogradov, A. A. Hamid, A. D. Redish (2022). Etiopathogenic models of psychosis spectrum illnesses must resolve four key features. Biological Psychiatry 92(6):514-522.
https://drive.google.com/file/d/175UjZ_m6i6ZjEsUgBvfbL66GCZDbzVwP/view?usp=sharing
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It looks like I missed last year. So I've also opened the 2022 ones. (3/4)
A.D. Redish, A. Kepecs, L. M. Anderson, O. Calvin, N. Grissom, A.F. Haynos, S. R. Heilbronner, A.B. Herman, S. Jacob, S. Ma, I. Vilares, S. Vinogradov, C.J. Walters, A.S. Widge, J.L. Zick, A. Zilverstand (2022) “Computational Validity: Using Computation to translate behaviors across species”. Philosophical Transactions of the Royal Society B 377:20200525.
https://drive.google.com/file/d/1cip_ukGdZ3C-p5ldh56UVMpvpOCgUZAe/view?usp=sharing
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It looks like I missed last year. So I've also opened the 2022 ones. (2/4)
A. F. Haynos, A. S. Widge, L. M. Anderson, A. D. Redish (2022) "Beyond description and deficits: How computational psychiatry can enhance an understanding of decision-making in anorexia nervosa" Current Psychiatry Reports. doi:/10.1007/s11920-022-01320-9.
https://drive.google.com/file/d/12wXuiwhQq07KI9qSpVibhevfMBfw7yoI/view?usp=sharing
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It looks like I missed last year. So I've also opened the 2022 ones. (1/4)
A.D. Redish, S.V. Abram, P.J. Cunningham, A.A. Duin, R. Durand-de Cuttoli, R. Kazinka, A. Kocharian, A.W. MacDonald III, B. Schmidt. N. Schmitzer-Torbert, M.J. Thomas, B.M. Sweis (2022) Sunk cost sensitivity during change-of-mind decisions is informed by both the spent and remaining costs. Communications Biology 5:1337.
https://drive.google.com/file/d/1bdetQEIzbu6Ic52IJxsSdos0Mrs6YOmB/view?usp=sharing
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Annual opening of the PDFs: Here are the 2023 papers from my laboratory (and our collaborations). 7/7
W. W. Pettine, D. V. Raman, A. D. Redish, J. D. Murray (2023) Human generalization of internal representations through prototype learning with goal-directed attention. Nature Human Behavior.
https://drive.google.com/file/d/1zW5XADSQ7A1Lzig0NuRg2YI2iW9sfplR/view?usp=drive_link
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Annual opening of the PDFs: Here are the 2023 papers from my laboratory (and our collaborations). 6/7
A. E. McLaughlin, A. D. Redish (2023) Optogenetic Disruption of the Prelimbic Cortex Alters Long-Term Decision Strategy but Not Valuation on a Spatial Delay Discounting Task. Neurobiology of Learning and Memory. 200:107734.
https://drive.google.com/file/d/1nyuQLlgS73mURgtIxqvZ03LM-FtofQYj/view?usp=sharing
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Annual opening of the PDFs: Here are the 2023 papers from my laboratory (and our collaborations). 5/7
E. B. Lind, B. M. Sweis, A. J. Asp, M. Esguerra, K. A. Silvia, A. D. Redish, M. J. Thomas (2023) A quadruple dissociation of reward-related behavior in mice across excitatory inputs to the nucleus accumbens shell. Communications Biology 6:119.
https://drive.google.com/file/d/1w-hUswi9g0fC8Y_84j2wyF_mU70aCR25/view?usp=sharing
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Annual opening of the PDFs: Here are the 2023 papers from my laboratory (and our collaborations). 5/7
E. B. Lind, B. M. Sweis, A. J. Asp, M. Esguerra, K. A. Silvia, A. D. Redish, M. J. Thomas (2023) A quadruple dissociation of reward-related behavior in mice across excitatory inputs to the nucleus accumbens shell. Communications Biology 6:119.
https://drive.google.com/file/d/1w-hUswi9g0fC8Y_84j2wyF_mU70aCR25/view?usp=sharing
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Annual opening of the PDFs: Here are the 2023 papers from my laboratory (and our collaborations). 4/7
D. Levenstein, V. A. Alvarez, A. Amarasingham, H. Azab, Z. S. Chen, R. C. Gerkin, A. Hasenstaub, R. Iyer, R. B. Jolivet, S. Marzen, J. D. Monaco, A. A. Prinz, S. Quraishi, F. Santamaria, S. Shivkumar, M. F. Singh, R. Traub, H. G. Rotstein, F. Nadim, A. D. Redish (2023) On the role of theory and modeling in neuroscience. Journal of Neuroscience 43.7 (2023): 1074-1088.
https://drive.google.com/file/d/1TACymPh0xbWzp6FjZo5QlVEGNRz3v22c/view?usp=sharing
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Annual opening of the PDFs: Here are the 2023 papers from my laboratory and our collaborations. 3/7
G. W. Diehl, A. D. Redish (2023) Differential processing of decision information in subregions of rodent medial prefrontal cortex. eLife 12:e82833.
https://drive.google.com/file/d/1FSuMk0e0Q53Ogl_axz7zAQMf9gFG7yo6/view?usp=sharing
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Annual opening of the PDFs: Here are the 2023 papers from my laboratory and our collaborations. 2/7
C. F. Runge, J. A. Johnson, E. A. Nelson, A. D. Redish (2023) A neuroscience-based analysis of impacts of disaster memory on economic valuation. Journal of Neuroscience, Psychology, and Economics 16(1):24-49.
https://drive.google.com/file/d/1BzSOgvoLTFwb8YKX0n92aHjNR7mgREWs/view?usp=sharing
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Annually, I post the final-version PDFs of papers that are at least a year old. (I choose to interpret the NIH rules as requiring they be shared after 12 months, so every year on 1/Jan, I open up all of the ones from last year.)
So here are the 2023 papers from my laboratory and our collaborations. 1/7
S. Kalhan, M. I. Garrido, R. Hester, A. D. Redish (2023). Reward prediction-errors weighted by cue salience produces addictive behaviors in simulations, with asymmetrical learning and steeper delay discounting. Neural Networks 168:631-651.
https://drive.google.com/file/d/1izexGZJboeuGKr6JfvgyW9OQdK7T5bis/view?usp=sharing
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@neuralreckoning
Agree 100% re team sizes.
Agree 100% re independence.
But disagree (respectfully) re progress on the debates.
We know that it's not "innate vs learned", but rather, an innate structure that is modified through learning in very complex (and actually relatively well understood [in some cases - such as corticothalamus, entorhinal-hippocampus, basal ganglia]).
We know that it's not spikes vs rates, but rather "how much can it shift and not matter".
On the cognitivism side, it's pretty well settled - cognitive wins! We have opened the black box and can see inside. We really can "read rat's minds and listen to their dreams". (And we can read human dreams too.) [To a limited extent.]
We've made tremendous progress over the last 100 years.
Importantly, I think that tremendous progress was made, in large part, because of small R01s, not big P-center grants, so yes, agree 100% re teams.
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Also, by the way, this paper contains the history of #VTE that I often use in my talks. (Updated to include not just the technological breakthroughs in experimental techniques and the mathematical sciences, but also the theoretical breakthroughs that were necessary to get us to see rats "thinking about the future".)
I think this speaks to why science is slow and why we have to look at science over a long time scale
[#]neuroscience #science #SlowScience
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