Toots for markjamesadams@genomic.social account

Written by Mark James Adams on 2025-01-30 at 07:06

Mac OS is not UNIX® because to be UNIX® the system has to operate like it is still 1994.

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Written by Mark James Adams on 2025-01-30 at 07:00

"So, if you want your installation of macOS 15.0 to pass the UNIX® 03 certification test suites, you need to disable System Integrity Protection, enable the root account, enable core file generation, disable timeout coalescing, mount any APFS partitions with the strictatime option…"

https://exquisite.social/@thomholwerda/113914033124355983

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Written by Mark James Adams on 2025-01-20 at 09:04

Resources for learning about assembly on Apple Silicon:

HelloSilicon: An introduction to ARM64 assembly on Apple Silicon Macs (tailoring of ARM assembly book code) https://github.com/below/HelloSilicon

AArch64-Explore: Exploration of Apple CPUs (code experiments and analysis of patents) https://github.com/name99-org/AArch64-Explore

Apple Silicon CPU Optimization Guide (overviews of instruction sets, SIMD, microarchitecture, cache topology) [developer login required] https://developer.apple.com/download/apple-silicon-cpu-optimization-guide/

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Written by Mark James Adams on 2025-01-14 at 16:21

My (and 377 coauthors) latest paper:

Genome-wide association study of major depressive disorder in more than half a million cases.

https://www.cell.com/cell/fulltext/S0092-8674(24)01415-6

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Written by Mark James Adams on 2024-12-11 at 20:58

I'm choosing to read this as saying users of Windows 2.0 can now install and run iA Writer. 😌

https://mastodon.social/@reichenstein/113636167017543478

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Written by Mark James Adams on 2024-11-20 at 21:21

My 8-year-old Linux workstation is quietly humming along just fine on Ubuntu 22.04 LTS.

https://arstechnica.com/gadgets/2024/11/microsoft-pushes-full-screen-ads-for-copilot-pcs-on-windows-10-users/

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Written by Mark James Adams on 2024-10-30 at 07:05

M4 Pro chip has "10 performance cores and four efficiency cores" (10P+4E), a change from the more balanced M3 Pro (6P+6E) and a return to ratios between the M2 Pro (8P+4E) and M1 Pro (8P+2E)

https://www.apple.com/newsroom/2024/10/apples-new-mac-mini-is-more-mighty-more-mini-and-built-for-apple-intelligence/

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Written by Mark James Adams on 2024-10-29 at 21:54

M4 Mac mini marketing materials have "DNA sequencing" as one of the performance comparisons.

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Written by Mark James Adams on 2024-10-09 at 07:28

When writing R, I ”tidyverse" by default. But if I'm editing someone's code and they only use base R, I’ll stick to it.

The “$”, “[“, and “]” keys are getting an extra workout this morning. #RStats

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Written by Mark James Adams on 2024-09-10 at 11:16

Ordnance Survey (UK) have added a 3D view to their online topographic maps 😍

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Written by Mark James Adams on 2024-09-06 at 06:11

Is there a geological explanation for the distribution of Tim Hortons in Scotland?

"The Highland Boundary Doughnut Line"

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Written by Mark James Adams on 2024-08-12 at 09:47

The UK government has shelved a proposed exascale supercomputer because “the previous government had not identified any funding for the pledge” 🤦

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Written by Mark James Adams on 2024-08-11 at 21:01

Someone is vastly underestimating academics’ appetency to not pay for things.

https://www.theregister.com/2024/08/08/anaconda_puts_the_squeeze_on/

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